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2C-I 2,5-dimethoxy-4-iodophenethylamine Minimize

2C-I also known as "smiles" is a psychedelic drug and phenethylamine of the 2C family. It was developed and popularized by Alexander Shulgin. The drug is used recreationally and as an entheogen but no medical or industrial uses have been reported yet. It is most commonly encountered in the form of its hydrochloride salt (a fluffy, sparkling white powder) and has also been pressed into tablet form.  2C-I (2,5-dimethoxy-4-iodophenethylamine) is classified as an illegal Schedule I drug in the United States (as of July 2012).


Side Effects and Adverse Reactions:

Users of 2C-I tend to report a physical stimulant effect, which is often quite strong. Although unpleasant physical side effects such as muscle tension, nausea, and vomiting have been reported, their incidence in the use of 2C-I appears to be less common than in the use of some of the other closely related phenethylamines such as 2C-T-2 and 2C-T-7.

Research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their side effects, adverse reactions, long term damage, addiction potential, etc. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.

Illicit Distribution:

2C-I is distributed as capsules, tablets, in powder form, or in liquid form. DEA identified occurrences of the drug being purchased through Internet retailers. In one instance, it was purchased in powder form through the Internet and encapsulated for retail, at a street value of $6 per capsule. In Europe, 2C-I has often been seized in tablet form with an 'i‟ logo which may be to signify that it is not ecstasy (MDMA).